Study trend Italian Multiple Sclerosis and Related Disorders Register (data at 29th May 2026)
All Patients: 99.625
SM Patients
98.530
98.530
NMOSD/MOGAD Patients
1.095
1.095
MOGAD
362
362
NMOSD AQP4-
257
257
NMOSD AQP4+
476
476
By hovering over the graphs you can view numbers or percentages.
SM PATIENTS
Distribution by gender
Distribution by age classes (age at 29th May 2026)
Symptoms at the onset
| Symptom | % Patient |
|---|---|
| Supratentorial | 19.48% |
| Optic | 19.69% |
| Spinal | 23.34% |
| Brainstem | 17.75% |
| Polysymptomatic | 11.3% |
| Other | 8.44% |
Distribution for symptoms at onset
First MS-Course
| MS-Course | % Patient |
|---|---|
| CIS | 87.9% |
| PP MS | 5.59% |
| Missing | 6.51% |
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
RR MS=Relapsing Remitting
Distribution First MS-Course
Last MS-Course
| MS-Course | % Pazienti |
|---|---|
| RR MS | 72.67% |
| SP MS | 10.72% |
| CIS | 4.51% |
| PP MS | 3.63% |
| PR MS | 1.96% |
| Missing | 6.51% |
RR MS=Relapsing Remitting;
SP MS=Secondary Progressive;
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
PR MS=Progressive Relapsing;
Distribution Last MS-Course
Classes of sex/age at onset
| Age class | % Male | % Female |
|---|---|---|
| 0-17 yy | 2% | 4.43% |
| 18-24 yy | 6.58% | 13.72% |
| 25-32 yy | 9.14% | 18.19% |
| 33-40 yy | 6.71% | 13.65% |
| 41-48 yy | 4.47% | 9.69% |
| 49-56 yy | 2.36% | 4.51% |
| 57-64 yy | 0.83% | 1.29% |
| >=65 yy | 0.22% | 0.33% |
| Missing data | 1.88% | |
Distribution of sex/age at onset
NMOSD/MOGAD PATIENTS
Pathology Details
| Description | N. Patients |
|---|---|
| MOGAD | 362 |
| NMOSD AQP4-negative | 257 |
| NMOSD AQP4-positive | 476 |